Description

Nilprazole is a high-purity chemical intermediate primarily utilized in advanced pharmaceutical synthesis. Its value lies in its specific reactivity, making it a critical building block for the development of novel active pharmaceutical ingredients (APIs). This product is essential for research institutions and manufacturers in the pharmaceutical and fine chemical sectors seeking reliable, high-quality raw materials for complex synthesis pathways. Nilprazole CAS NO 60662-19-3 is supplied to meet the stringent demands of global industrial and research applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of proton pump inhibitors (PPIs) and other specialized therapeutic agents.
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds and novel molecular entities.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring precise chemical transformations.
• Biochemical Research: Serves as a reagent in studies exploring enzyme inhibition and metabolic pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of APIs.

Basic Information

Product Name	Nilprazole
CAS No.	60662-19-3
Molecular Formula	C16H14F3N3O2S
Molecular Weight	393.36 g/mol
Synonyms	2-[[(3,5-Dimethyl-4-methoxy-2-pyridinyl)methyl]sulfinyl]-5-(trifluoromethyl)-1H-benzimidazole; AG-1749; AG1749; Lansoprazole Impurity; Lansoprazole Related Compound A; 5-Trifluoromethyl-2-[[(3,5-dimethyl-4-methoxypyridin-2-yl)methyl]sulfinyl]-1H-benzimidazole
EINECS	Contact for details

Quality Control

Our Nilprazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, IR, and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.