Description

Bifonazole CAS NO 60628-96-8 is a synthetic, broad-spectrum azole antifungal agent known for its potent activity against dermatophytes, yeasts, and molds. Its primary value lies in its high efficacy and stability, making it a critical active pharmaceutical ingredient (API) for topical antifungal formulations. This compound is essential for manufacturers in the pharmaceutical and personal care industries developing products to treat fungal skin infections such as athlete's foot, ringworm, and candidiasis.

Application

• Pharmaceutical API: Primary active ingredient in topical creams, ointments, powders, and sprays for treating dermatomycoses.
• Antifungal Creams & Ointments: Used in over-the-counter (OTC) and prescription medications for tinea pedis, tinea corporis, and tinea cruris.
• Veterinary Pharmaceuticals: Incorporated into topical treatments for fungal infections in animals.
• Personal Care Products: Key component in medicated foot care powders, antifungal soaps, and specialized hygiene products.
• Research & Development: Serves as a reference standard and building block in microbiological and pharmacological research for novel antifungal agents.

Basic Information

Product Name	Bifonazole
CAS No.	60628-96-8
Molecular Formula	C22H18N2
Molecular Weight	310.40 g/mol
Synonyms	1-[(1,1'-Biphenyl)-4-ylphenylmethyl]-1H-imidazole; Bifonazol; Mycospor; Azolmen; Bifazole; Bay h 4502; (RS)-1-(4,4'-Biphenylyl)phenylmethyl-1H-imidazole
EINECS	262-326-6

Quality Control

Our Bifonazole is manufactured under strict quality management systems to meet the rigorous standards required for pharmaceutical actives. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and related substances tests. We ensure compliance with relevant pharmacopeial guidelines (e.g., EP, USP) where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.