Description

2-[3-(Trifluoromethyl)Phenoxy]Butanoyl Chloride is a specialized organic intermediate featuring a reactive acid chloride group and a trifluoromethylphenoxy moiety. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the incorporation of a trifluoromethylphenyl ether group to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds due to its specific aromatic and fluorinated structure.
• Polymer Modification: Employed to introduce functional side chains into polymers, altering their physical properties for specialized coatings or high-performance materials.
• Custom Synthesis & Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Phenoxy]Butanoyl Chloride
CAS No.	60626-15-5
Molecular Formula	C11H10ClF3O2
Molecular Weight	266.64 g/mol
Synonyms	2-[3-(Trifluoromethyl)phenoxy]butanoyl chloride; Butanoyl chloride, 2-[3-(trifluoromethyl)phenoxy]-; α-Phenoxybutyryl chloride, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)phenoxybutyryl chloride; 2-(3-Trifluoromethylphenoxy)butyryl chloride; 2-(m-Trifluoromethylphenoxy)butyric acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2-[3-(Trifluoromethyl)Phenoxy]Butanoyl Chloride is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.