Description

Pinacidil is a potent and selective potassium channel activator belonging to the cyanoguanidine class of compounds. This high-purity pharmaceutical intermediate is critical for research and development in cardiovascular pharmacology and metabolic studies. It is primarily utilized by pharmaceutical manufacturers, biotechnology research firms, and academic institutions engaged in drug discovery and physiological mechanism studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced investigational drugs targeting hypertension and angina.
• Cardiovascular Research: Used as a reference standard and active agent in preclinical studies to investigate vasodilation, smooth muscle relaxation, and cardioprotective mechanisms.
• Metabolic Disorder Studies: Employed in research models to study potassium channel function in relation to insulin secretion and potential treatments for diabetes.
• Biochemical Tool Compound: Serves as a selective KATP channel opener in electrophysiology and cell signaling pathway analysis.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Product Name	Pinacidil
CAS No.	60560-33-0
Molecular Formula	C13H19N5
Molecular Weight	245.33 g/mol
Synonyms	P1134; (±)-Pinacidil; Pinacidil Monohydrate; N"-Cyano-N-4-pyridyl-N'-1,2,2-trimethylpropylguanidine; 2-Cyano-1-[(4-pyridyl)amino]-3,3-dimethylguanidine; 3,3-Dimethyl-1-(4-pyridylamino)-2-cyanoguanidine; 1-[(4-Pyridyl)amino]-2-cyano-3,3-dimethylguanidine
EINECS	Contact for details

Quality Control

Our Pinacidil is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.