Description

5-Chloro-2-Ethoxybenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 5-chloro-2-ethoxybenzoyl moiety into target molecules, enabling the creation of complex chemical architectures. This intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and plant growth regulators, where the chlorinated ethoxybenzene structure confers specific biological activity.
• Liquid Crystal & Dye Manufacturing: Serves as a building block for advanced organic materials, including liquid crystal displays (LCDs) and specialized organic pigments.
• Peptide Coupling & Amide Formation: An effective acylating agent for the preparation of amides and peptides under mild conditions in research and development.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where it acts as a monomer or cross-linking agent.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse client projects.

Basic Information

Product Name	5-Chloro-2-Ethoxybenzoyl Chloride
CAS No.	60531-34-2
Molecular Formula	C9H8Cl2O2
Molecular Weight	219.07 g/mol
Synonyms	2-Ethoxy-5-chlorobenzoyl chloride; 5-Chloro-2-ethoxybenzoic acid chloride; 5-Chloro-o-ethoxybenzoyl chloride; Benzoic acid, 5-chloro-2-ethoxy-, chloride; 60531-34-2; NSC 403119
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Ethoxybenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC for purity and IR & NMR for structural confirmation to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and reacts with water and alcohols; ensure containers are kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid / crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.