Description

3,3-Dimethylspiro[Cyclopropane-1,1'-[1H]Indene]-2-Carbonyl Chloride is a specialized spirocyclic acid chloride building block used in advanced organic synthesis. This compound matters for its unique fused ring structure, which serves as a critical precursor for constructing complex molecular architectures with potential biological activity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its spirocyclic framework for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with unique thermal or mechanical properties.
• Chemical Biology: Employed as a probe or linker in the study of protein-ligand interactions and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry, including studies on cyclopropanation and spiroannulation reactions.

Basic Information

Product Name	3,3-Dimethylspiro[Cyclopropane-1,1'-[1H]Indene]-2-Carbonyl Chloride
CAS No.	60450-40-0
Molecular Formula	C14H13ClO
Molecular Weight	232.70 g/mol
Synonyms	2-(3,3-Dimethylspiro[cyclopropane-1,1'-indene]-2-carbonyl) chloride; 1H-Indene-1-carbonyl chloride, 2,3-dihydro-3,3-dimethylspiro[cyclopropane-1,1'-[1H]inden]-2'-yl-; Spiro[cyclopropane-1,1'-[1H]indene]-2-carbonyl chloride, 3,3-dimethyl-; 3,3-Dimethylspiro[cyclopropane-1,1'-indene]-2-carbonyl chloride; 60450-40-0; Spirocyclic acid chloride
EINECS	Contact for details

Quality Control

Our 3,3-Dimethylspiro[Cyclopropane-1,1'-[1H]Indene]-2-Carbonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.