Description

Natamycinolide is a high-purity chemical intermediate and reference standard derived from the polyene macrolide antibiotic natamycin. This compound is critical for research and development in pharmaceutical and agrochemical synthesis, serving as a key building block for novel antimicrobial agents. It is primarily utilized by R&D chemists, analytical laboratories, and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors seeking to develop or quality-control advanced formulations.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel antifungal and antibiotic derivatives.
• Analytical Reference Standard: Used in HPLC, LC-MS, and NMR for method development, validation, and quality control of natamycin and related compounds.
• Biochemical Research: Employed in microbiological and pharmacological studies to investigate structure-activity relationships (SAR) of polyene macrolides.
• Agrochemical Development: Acts as a starting material for creating new crop protection agents with antifungal properties.
• Veterinary Medicine: Utilized in R&D for developing antifungal treatments in animal health.
• Food Preservative Research: Investigated for developing next-generation, natural preservative systems in food science.

Basic Information

Product Name	Natamycinolide
CAS No.	60395-07-5
Molecular Formula	C33H47NO13
Molecular Weight	665.73 g/mol
Synonyms	Natamycin Impurity C; Pimaricin Lactone; 22,23-Dihydro-29-demethyl-29-deoxynatamycin; Natamycin Lactone; Natamycinolide A; Natamycin degradation product; (1R,3S,5R,7R,8E,12R,14E,16E,18E,20R,21R,24S,25R,26S)-25-[(2S,3S,4S,5S)-3,4-Dihydroxy-5-methyltetrahydrofuran-2-yl]-5,21,26-trihydroxy-3-[(1R)-1-hydroxyethyl]-1,7,12,24-tetramethyl-9-oxo-6,28-dioxabicyclo[22.2.1]heptacosa-8,14,16,18-tetraene-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our Natamycinolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with internal quality standards and regulatory readiness.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.