Description

3α,7α,12α-Triacetoxy-5α-Cholan-24-Oic Acid Methyl Ester is a key cholic acid derivative and a critical synthetic intermediate in the production of bile acids and their analogs. This high-purity compound is essential for researchers and manufacturers requiring precise chemical building blocks for pharmaceutical development and biochemical studies. It is primarily utilized in the synthesis of therapeutic agents, diagnostic reagents, and advanced biochemical research materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of ursodeoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), and other therapeutic bile acids.
• Biochemical Research: Used as a standard or reagent in studies related to cholesterol metabolism, liver function, and bile acid signaling pathways.
• Diagnostic Reagent Synthesis: Serves as a starting material for producing conjugated bile acids used in clinical diagnostic kits and assays.
• Steroid Chemistry: A versatile building block for the chemical modification and synthesis of various steroid derivatives with potential biological activity.
• Reference Standard: Employed as a high-purity reference standard in quality control (QC) and analytical laboratories for HPLC or LC-MS methods.
• Academic & Industrial R&D: Facilitates exploratory research in medicinal chemistry and the development of new drug candidates targeting metabolic and digestive disorders.

Basic Information

Item	Details
Product Name	3α,7α,12α-Triacetoxy-5α-Cholan-24-Oic Acid Methyl Ester
CAS No.	60384-35-2
Molecular Formula	C31H48O8
Molecular Weight	548.71 g/mol
Synonyms	Methyl 3α,7α,12α-triacetoxy-5α-cholan-24-oate; 5α-Cholan-24-oic acid, 3,7,12-triacetoxy-, methyl ester, (3α,5α,7α,12α)-; Methyl 3α,7α,12α-triacetoxy-5α-cholanate; Cholic acid triacetate methyl ester; 3α,7α,12α-Triacetoxycholanoic acid methyl ester; Methyl triacetoxycholanate
EINECS	Contact for details

Quality Control

Our 3α,7α,12α-Triacetoxy-5α-Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.