Description

24-Nor-5β-Chol-22-Ene-3α,7α,12α-Triol Triacetate is a high-purity, semi-synthetic steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and reference standard for the study of bile acid metabolism and related biochemical pathways. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of novel therapeutics and diagnostic agents. The compound is supplied with full analytical documentation to ensure reliability and reproducibility in sensitive applications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and bioactive molecules targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard and precursor in studies investigating bile acid biosynthesis, transport, and receptor interactions.
• Metabolite Synthesis: Employed in the preparation of specific nor-bile acid metabolites for pharmacokinetic and metabolic profiling studies.
• Diagnostic Agent Development: Serves as a starting material for creating labeled compounds (e.g., with isotopes or fluorescent tags) used in diagnostic assays and imaging.
• Enzyme Inhibition Studies: Utilized to probe the activity and specificity of enzymes involved in steroid and bile acid modification pathways.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in medicinal chemistry and steroid biology.

Basic Information

Item	Details
Product Name	24-Nor-5β-Chol-22-Ene-3α,7α,12α-Triol Triacetate
CAS No.	60354-49-6
Molecular Formula	C₂₉H₄₄O₆
Molecular Weight	488.66 g/mol
Synonyms	3α,7α,12α-Triacetoxy-24-nor-5β-chol-22-ene; 24-Norchol-22-ene-3α,7α,12α-triol, triacetate; 24-Nor-5β-chol-22-ene-3α,7α,12α-triol triacetate; 3α,7α,12α-Trihydroxy-24-nor-5β-chol-22-en-24-oic Acid Triacetate (lactone form); Norcholene Triacetate Derivative; Bile Acid Nor-Derivative Triacetate; 24-Nor-5β-cholen-22-ene-3α,7α,12α-triol triacetate
EINECS	Contact for details

Quality Control

Every batch of 24-Nor-5β-Chol-22-Ene-3α,7α,12α-Triol Triacetate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.