Description

3α,11α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is a high-purity, synthetic steroid derivative and a key advanced intermediate in organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for the research and development of complex bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and synthesizing new chemical entities (NCEs) for biological evaluation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid compounds.
• Biochemical Research: Utilized in studies investigating steroid hormone pathways, receptor interactions, and metabolic processes.
• Fine Chemical Synthesis: Acts as a starting material for the production of specialized cholanic acid derivatives and other high-value, low-volume specialty chemicals.

Basic Information

Product Name	3α,11α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester
CAS No.	60354-48-5
Molecular Formula	C₂₈H₄₄O₆
Molecular Weight	476.65 g/mol
Synonyms	Methyl 3α,11α-Diacetoxy-24-nor-5β-cholan-23-oate; 24-Norcholan-23-oic acid, 3,11-bis(acetyloxy)-, methyl ester, (3α,5β,11α)-; 3α,11α-Diacetoxy-24-nor-5β-cholan-23-oic Acid Methyl Ester; Methyl 3α,11α-dihydroxy-24-nor-5β-cholan-23-oate diacetate; 24-Nor-5β-cholan-23-oic Acid Methyl Ester 3α,11α-diacetate
EINECS	Contact for details

Quality Control

Our 3α,11α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect the product from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.