Description

3α,12α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. This compound is valued for its defined chemical structure, enabling precise modifications in the synthesis of novel therapeutic agents and reference standards. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of steroidal drugs, metabolic studies, and high-value fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal active pharmaceutical ingredients (APIs) and potential drug candidates.
• Research Chemical: Used in academic and industrial R&D for studying steroid metabolism, receptor interactions, and structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in laboratories.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value cholanic acid derivatives for various investigational applications.
• Biochemical Tool: Utilized in metabolic pathway research and as a probe in biochemical assays related to bile acid and steroid biology.

Basic Information

Product Name	3α,12α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester
CAS No.	60354-47-4
Molecular Formula	C₂₈H₄₄O₆
Molecular Weight	476.65 g/mol
Synonyms	Methyl 3α,12α-Diacetoxy-24-nor-5β-cholan-23-oate; 24-Nor-5β-cholan-23-oic Acid, 3,12-Bis(acetyloxy)-, Methyl Ester, (3α,5β,12α)-; 3α,12α-Diacetoxy-24-nor-5β-cholan-23-oic Acid Methyl Ester; Methyl 3α,12α-diacetoxy-24-nor-5β-cholanate; 24-Norcholanic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3α,12α-Bis(Acetyloxy)-24-Nor-5β-Cholan-23-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.