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3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide CAS NO 60344-07-2
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CAS No.:60344-07-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents targeting cardiovascular function. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and pharmacology.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of novel cardiac glycosides and related cardioactive drugs.
- Medicinal Chemistry Research: Used as a reference standard or precursor in structure-activity relationship (SAR) studies for heart failure treatments.
- Biochemical Research: Investigation of sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition mechanisms and ion channel modulation.
- Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
- Academic Studies: Utilized in university and institutional research exploring natural product derivatives and their biological activities.
Basic Information
| Product Name | 3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide |
| CAS No. | 60344-07-2 |
| Molecular Formula | C₃₀H₄₆O₉ |
| Molecular Weight | 550.68 g/mol |
| Synonyms | 3β-[(3-O-Methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-11α,14-dihydroxy-5β-card-20(22)-enolide; 3-O-Methyldigitoxigenin β-L-Diginoside; 3β-[(3-O-Methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; 11α,14-Dihydroxy-3β-[(3-O-methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-5β-card-20(22)-enolide; Cardiac glycoside derivative; 3-O-Methyldigitoxigenin L-diginoside; 3-O-Methylgitoxigenin α-L-diginoside; 3-O-Methylgitoxigenin β-L-diginoside |
| EINECS | Contact for details |
Quality Control
Our 3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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