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3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide CAS NO 60344-07-2


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CAS No.:60344-07-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role in the research and development of novel therapeutic agents targeting cardiovascular function. It is primarily needed by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and pharmacology.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel cardiac glycosides and related cardioactive drugs.
  • Medicinal Chemistry Research: Used as a reference standard or precursor in structure-activity relationship (SAR) studies for heart failure treatments.
  • Biochemical Research: Investigation of sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition mechanisms and ion channel modulation.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Academic Studies: Utilized in university and institutional research exploring natural product derivatives and their biological activities.

Basic Information

Product Name 3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide
CAS No. 60344-07-2
Molecular Formula C₃₀H₄₆O₉
Molecular Weight 550.68 g/mol
Synonyms 3β-[(3-O-Methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-11α,14-dihydroxy-5β-card-20(22)-enolide; 3-O-Methyldigitoxigenin β-L-Diginoside; 3β-[(3-O-Methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; 11α,14-Dihydroxy-3β-[(3-O-methyl-2,6-dideoxy-α-L-arabino-hexopyranosyl)oxy]-5β-card-20(22)-enolide; Cardiac glycoside derivative; 3-O-Methyldigitoxigenin L-diginoside; 3-O-Methylgitoxigenin α-L-diginoside; 3-O-Methylgitoxigenin β-L-diginoside
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Quality Control

Our 3β-[(3-o-Methyl-2,6-Dideoxy-L-Arabino-Hexopyranosyl)Oxy]-11α,14-Dihydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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