Description

(3A,5A,7A,12A)-Cholestane-3,7,12,25-Tetrol is a high-purity, polyhydroxylated sterol derivative, a key intermediate in the synthesis of complex bile acids and other bioactive steroids. Its precise stereochemistry and defined hydroxylation pattern make it a critical building block for pharmaceutical research and development, particularly in metabolic and liver disease studies. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring high-quality steroidal intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of therapeutic bile acids and steroid-based drug candidates targeting liver and metabolic disorders.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies related to cholesterol metabolism and bile acid biosynthesis pathways.
• Metabolite Synthesis: Employed in the preparation of labeled or modified sterol metabolites for pharmacokinetic and metabolic profiling studies.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the production of complex, high-value steroidal compounds in custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for investigating the structure-activity relationships of hydroxylated sterols.

Basic Information

Product Name	(3A,5A,7A,12A)-Cholestane-3,7,12,25-Tetrol
CAS No.	60257-29-6
Molecular Formula	C27H48O4
Molecular Weight	436.67 g/mol
Synonyms	3α,7α,12α,25-Tetrahydroxycholestane; 5β-Cholestane-3α,7α,12α,25-tetrol; 25-Hydroxycholic Acid Precursor; 3α,7α,12α,25-Tetrahydroxy-5β-cholestane; Cholestanetetrol; Tetrahydroxycholestane
EINECS	Contact for details

Quality Control

Our (3A,5A,7A,12A)-Cholestane-3,7,12,25-Tetrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.