Description

N1-Methyl-2'-Deoxyadenosine CAS NO 60192-55-4 is a chemically modified nucleoside analog, specifically a methylated derivative of deoxyadenosine. This modification is critical for research into nucleic acid structure, function, and as a building block for oligonucleotide synthesis. It serves as a valuable biochemical tool for scientists in pharmaceutical discovery and molecular biology. Key industries that utilize this compound include biotechnology research, diagnostic development, and academic institutions.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving methyltransferases and other nucleic acid-modifying enzymes.
• Oligonucleotide Synthesis: Acts as a modified building block (phosphoramidite) for the solid-phase synthesis of DNA strands with specific methylation patterns.
• Epigenetics Studies: Employed in research investigating DNA methylation and its role in gene expression regulation and disease mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery of novel antiviral or anticancer nucleoside analogs.
• Diagnostic Probe Development: Utilized in the creation of labeled probes for detecting specific DNA sequences or methylation status.
• Academic Research: A fundamental reagent for university laboratories studying nucleic acid chemistry and molecular biology.

Basic Information

Product Name	N1-Methyl-2'-Deoxyadenosine
CAS No.	60192-55-4
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	1-Methyl-2'-deoxyadenosine; N(1)-Methyl-2'-deoxyadenosine; 1-Methyladenosine 2'-deoxyriboside; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-1-methyladenine; 2'-Deoxy-1-methyladenosine; dA(1-Me); 1-Me-dA
EINECS	Contact for details

Quality Control

Our N1-Methyl-2'-Deoxyadenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.