Description

5-Formyluridine-5'-Monophosphate is a chemically modified nucleotide monophosphate, serving as a critical building block and research reagent in advanced biochemical synthesis. This compound is essential for studying nucleic acid structure, function, and for the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on nucleoside chemistry, antiviral research, and oligonucleotide synthesis.

Application

• Biochemical Research: A key intermediate in the study of nucleic acid modification, structure-activity relationships, and enzymatic processes.
• Pharmaceutical Development: Used in the research and synthesis of novel nucleoside-based antiviral and anticancer prodrug candidates.
• Oligonucleotide Synthesis: Serves as a modified phosphoramidite precursor for incorporating unique functionalities into synthetic DNA and RNA strands.
• Enzymology Studies: Employed as a substrate or inhibitor to investigate the mechanisms of kinases, phosphorylases, and other nucleotide-processing enzymes.
• Diagnostic Probe Development: Utilized in creating labeled probes for detecting specific nucleic acid sequences in research assays.

Basic Information

Product Name	5-Formyluridine-5'-Monophosphate
CAS No.	60170-17-4
Molecular Formula	C10H13N2O10P
Molecular Weight	352.19 g/mol
Synonyms	5-Formyluridine 5'-monophosphate; 5-Formyl-UMP; 5-FoUMP; 5-Carboxyaldehydeuridine monophosphate; Uridine, 5-formyl-, 5'-(dihydrogen phosphate); 5-Formyluridylic acid; 5-Formyl-2'-deoxyuridine 5'-monophosphate (common misnomer, verify structure); 5-FordUMP
EINECS	Contact for details

Quality Control

Our 5-Formyluridine-5'-Monophosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccation and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.