Description

N4-Propanoylcytidine CAS NO 60107-04-2 is a chemically modified nucleoside derivative, specifically a cytidine analog where the N4 position is acylated with a propanoyl group. This modification is critical for altering the nucleoside's biological activity and physicochemical properties, making it a valuable intermediate in advanced research and development. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of modified oligonucleotides for therapeutic and diagnostic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and processing.
• Oligonucleotide Synthesis: Serves as a modified monomer for incorporating specific functionalities into DNA or RNA strands to enhance stability or binding affinity.
• Proteomics & Molecular Biology: Potential use in labeling or cross-linking applications for studying nucleic acid-protein interactions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	N4-Propanoylcytidine
CAS No.	60107-04-2
Molecular Formula	C12H17N3O6
Molecular Weight	299.28 g/mol
Synonyms	N4-Propionylcytidine; Cytidine, N4-propanoyl-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-4-(propanoylamino)pyrimidin-2-one; 4-N-Propanoylcytidine; N4-Propionylcytidine; Propanoylcytidine; 4-(Propionylamino)-1-β-D-ribofuranosyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Every batch of N4-Propanoylcytidine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research and development applications, with specifications typically meeting or exceeding 95% purity by HPLC. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.