Description

Crotonyl Isothiocyanate is a versatile organic building block characterized by its reactive isothiocyanate functional group. This compound is essential for synthesizing a wide range of heterocyclic compounds and functional materials, offering chemists a key handle for introducing sulfur and nitrogen-containing moieties. It is particularly valuable for researchers and manufacturers in the agrochemical, pharmaceutical, and specialty chemical industries seeking to develop novel active ingredients or advanced intermediates.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its bioactivity.
• Pharmaceutical Research: Used in medicinal chemistry for creating potential drug candidates, especially those targeting specific enzymes or receptors.
• Heterocyclic Chemistry: Serves as a crucial reagent for constructing various sulfur and nitrogen-containing heterocycles like thiazoles and thiadiazoles.
• Polymer Modification: Employed to introduce functional isothiocyanate groups into polymer chains, altering material properties for specialty applications.
• Ligand Synthesis: Useful for preparing specialized ligands used in catalysis and metal complexation studies.
• Bioconjugation: Potential use in biochemical research for labeling proteins or other biomolecules due to its reactivity with amines.

Basic Information

Product Name	Crotonyl Isothiocyanate
CAS No.	60034-28-8
Molecular Formula	C5H5NOS
Molecular Weight	127.16 g/mol
Synonyms	(E)-Crotonyl isothiocyanate; (E)-But-2-enoyl isothiocyanate; trans-Crotonyl isothiocyanate; 2-Butenoyl isothiocyanate; Crotonic acid isothiocyanate; Isothiocyanic acid crotonyl ester; NSC 404083
EINECS	Contact for details

Quality Control

Our Crotonyl Isothiocyanate is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.