Description

4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]Olivomycin D is a structurally complex, semi-synthetic derivative of the olivomycin family of antibiotics, valued for its potent biological activity and utility as a key reference standard and research intermediate. This compound is critical for advancing studies in oncology and microbiology, particularly in the investigation of DNA-binding agents and novel therapeutic mechanisms. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in the development of new anti-cancer and antimicrobial agents.

Application

• Pharmaceutical Research & Development: Serves as a crucial reference standard and building block in the synthesis and biological evaluation of novel anti-cancer compounds.
• Oncology Studies: Used in biochemical and cellular assays to study its mechanism of action as a DNA intercalator and inhibitor of topoisomerase II.
• Antimicrobial Research: Investigated for its potential activity against various bacterial and fungal strains, contributing to the search for new antibiotics.
• Biochemical Tool Compound: Employed in molecular biology to probe protein-DNA interactions and understand the structural requirements for DNA binding affinity.
• Process Chemistry & Scale-up: Acts as a key intermediate for process chemists developing scalable synthetic routes for complex glycopeptide antibiotics.
• Analytical Method Development: Utilized as a high-purity standard for developing and validating HPLC, LC-MS, and other chromatographic methods in quality control laboratories.

Basic Information

Product Name	4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]Olivomycin D
CAS No.	6988-59-6
Molecular Formula	C54H74O20
Molecular Weight	1043.15 g/mol
Synonyms	4''''-Deacetyl-3'''-O-[3-C-methyl-4-O-(2-methyl-1-oxopropyl)-2,6-dideoxy-α-L-arabino-hexopyranosyl]olivomycin D; Olivomycin D derivative; 3'''-O-(3-C-Methyl-4-O-isobutyryl-2,6-dideoxy-α-L-arabino-hexopyranosyl)-4''''-deacetylolivomycin D; Antibiotic U-12898; Isobutyryl-olivomycin D derivative
EINECS	Contact for details

Quality Control

Every batch of 4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]Olivomycin D is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when possible to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.