Description

3Beta,5,14,16Beta-Tetrahydroxy-19-Oxo-5Betacard-20(22)-Enolide 16-Acetate is a high-purity, specialized cardiac glycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel cardioactive agents and other steroidal molecules. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality building blocks for drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of novel cardiac glycosides and other steroidal pharmaceuticals.
• Reference Standard: Used as a certified reference material (CRM) for quality control, analytical method development, and validation in pharmaceutical laboratories.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of cardenolides and their interaction with biological targets like Na+/K+-ATPase.
• Process Chemistry: Utilized in route scouting and optimization for the scalable synthesis of complex steroidal active pharmaceutical ingredients (APIs).
• Metabolite Studies: Acts as a standard or starting material for the synthesis and identification of potential drug metabolites.

Basic Information

Item	Details
Product Name	3Beta,5,14,16Beta-Tetrahydroxy-19-Oxo-5Betacard-20(22)-Enolide 16-Acetate
CAS No.	6980-15-0
Molecular Formula	C₂₇H₃₈O₉
Molecular Weight	506.59 g/mol
Synonyms	16-Acetyl Gitoxin; 16-Acetylgitoxin; 3β,5,14,16β-Tetrahydroxy-19-oxo-5β,14β-card-20(22)-enolide 16-acetate; 16-O-Acetylgitoxin; Gitoxin 16-acetate; 5β,14β-Card-20(22)-enolide, 3,5,14,16-tetrahydroxy-19-oxo-, 16-acetate, (3β)-; 6980-15-0; 16-Acetyl-3β,5,14,16β-tetrahydroxy-19-oxo-5β,14β-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3Beta,5,14,16Beta-Tetrahydroxy-19-Oxo-5Betacard-20(22)-Enolide 16-Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.