Description

19-Oxo-3β,5,14-Trihydroxy-5β-Carda-16,20(22)-Dienolide is a high-purity cardenolide derivative, a class of compounds known for their significant biological activity. This compound serves as a critical advanced intermediate and reference standard in pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for the synthesis of novel therapeutic agents and for analytical purposes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Reference Standard: Used for quality control, method validation, and calibration in analytical laboratories (HPLC, LC-MS).
• Biochemical Research: Employed in studies investigating sodium-potassium ATPase inhibition and related cardiac cell signaling pathways.
• Preclinical Development: Serves as a starting material or metabolite analog in the development of new cardiovascular and oncological therapeutics.
• Academic Research: Utilized in universities and research institutes for pharmacological and chemical studies on natural product derivatives.

Basic Information

Product Name	19-Oxo-3β,5,14-Trihydroxy-5β-Carda-16,20(22)-Dienolide
CAS No.	6980-14-9
Molecular Formula	C₂₃H₃₂O₆
Molecular Weight	404.50 g/mol
Synonyms	19-Oxocardenolide; 3β,5,14-Trihydroxy-19-oxo-5β-card-16,20(22)-dienolide; 19-Oxodigitoxigenin; 19-Oxo-3β,5,14-trihydroxy-5β,14β-card-16,20(22)-dienolide; 19-Ketodigitoxigenin; 3β,5,14-Trihydroxy-19-oxocarda-16,20(22)-dienolide; 19-Oxocardenolide; 6980-14-9
EINECS	Contact for details

Quality Control

Our 19-Oxo-3β,5,14-Trihydroxy-5β-Carda-16,20(22)-Dienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.