Description

7-Chloro-3-β-D-Ribofuranosyl-3H-Imidazo[4,5-B]Pyridine is a key nucleoside analog building block with significant importance in advanced pharmaceutical research and development. Its core value lies in its role as a sophisticated synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly within the field of modified nucleosides. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and related biological pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of therapeutic molecules.
• Antiviral Agent Development: A precursor in the research and synthesis of potential agents targeting viral polymerases and replication mechanisms.
• Oncology Research: Investigated for incorporation into oligonucleotides or prodrugs designed to selectively target cancer cells.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a protected or functionalized imidazopyridine nucleoside.

Basic Information

Product Name	7-Chloro-3-β-D-Ribofuranosyl-3H-Imidazo[4,5-B]Pyridine
CAS No.	6980-13-8
Molecular Formula	C11H12ClN3O4
Molecular Weight	285.68 g/mol
Synonyms	7-Chloro-3-β-D-ribofuranosyl-3H-imidazo[4,5-b]pyridine; 7-Chloro-3-(β-D-ribofuranosyl)imidazo[4,5-b]pyridine; 3-β-D-Ribofuranosyl-7-chloroimidazo[4,5-b]pyridine; 7-Chloro-3-β-D-ribofuranosylimidazo[4,5-b]pyridine; 7-Chloro-3-(β-D-ribofuranosyl)-3H-imidazo[4,5-b]pyridine; Imidazo[4,5-b]pyridine, 7-chloro-3-β-D-ribofuranosyl-; 6980-13-8 (CAS)
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-β-D-Ribofuranosyl-3H-Imidazo[4,5-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.