Description

2',3',5'-Triacetylguanosine is a key protected nucleoside derivative, specifically the triacetylated form of guanosine. This chemical intermediate is crucial for the controlled synthesis of oligonucleotides and modified nucleosides, offering enhanced stability and solubility for advanced research and manufacturing processes. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic institutions engaged in nucleic acid chemistry, antiviral drug development, and proteomics research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of DNA and RNA sequences.
• Biochemical Research: Serves as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Proteomics & Diagnostics: Employed in the development of labeled probes and tools for genetic analysis and diagnostic assays.
• Academic & R&D: Fundamental research reagent for studying nucleic acid structure, function, and drug-nucleic acid interactions.

Basic Information

Product Name	2',3',5'-Triacetylguanosine
CAS No.	6979-94-8
Molecular Formula	C16H19N5O8
Molecular Weight	409.35 g/mol
Synonyms	Guanosine 2',3',5'-triacetate; 9-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one; 2',3',5'-Tri-O-acetylguanosine; N2-Acetylguanosine triacetate; Triacetyl guanosine; Guanosine triacetate; Protected guanosine
EINECS	Contact for details

Quality Control

Our 2',3',5'-Triacetylguanosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.