Description

16α-Hydroxy-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-One is a high-purity, structurally complex steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of steroidal drugs and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal drugs targeting hormone receptors.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing.
• Biochemical Research: Employed in academic and industrial research to study steroid hormone metabolism, receptor binding, and biological activity.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral to the production pathway of complex active pharmaceutical ingredients with modified steroidal backbones.

Basic Information

Product Name	16α-Hydroxy-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-One
CAS No.	6908-25-4
Molecular Formula	C₂₅H₄₁NO₂
Molecular Weight	387.60 g/mol
Synonyms	16α-Hydroxy-4,4,14-trimethyl-3β-(methylamino)-9β,19-cyclo-5α-pregnan-20-one; 3β-(Methylamino)-16α-hydroxy-4,4,14-trimethyl-9β,19-cyclo-5α-pregnan-20-one; 9β,19-Cyclo-5α-pregnan-20-one, 16α-hydroxy-4,4,14-trimethyl-3β-(methylamino)-; 16α-Hydroxy-4,4,14-trimethyl-3β-methylamino-9β,19-cyclo-5α-pregnan-20-one
EINECS	Contact for details

Quality Control

Our 16α-Hydroxy-4,4,14-Trimethyl-3β-(Methylamino)-9β,19-Cyclo-5α-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.