Description

5-α-Pregnan-3-Alpha, 17-Diol-20-One is a high-purity steroid derivative, also known as 5α-Pregnan-3α,17α-diol-20-one, serving as a critical intermediate in advanced pharmaceutical synthesis. Its value lies in providing a structurally defined backbone for the development of specialized therapeutic agents, including neurosteroids and hormone modulators. This compound is essential for research institutions and pharmaceutical manufacturers focused on endocrinology, neurology, and the production of reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of neuroactive steroids and other specialized therapeutic agents.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid metabolism, receptor interactions, and endocrine pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development of novel steroid-based APIs.
• Academic & Industrial R&D: Utilized in discovery research for new drug candidates targeting the central nervous system and hormonal systems.

Basic Information

Product Name	5-α-Pregnan-3-Alpha, 17-Diol-20-One
CAS No.	6890-65-9
Molecular Formula	C21H34O3
Molecular Weight	334.49 g/mol
Synonyms	5α-Pregnan-3α,17α-diol-20-one; 3α,17α-Dihydroxy-5α-pregnan-20-one; 17α-Hydroxypregnanolone; Allopregnanolone precursor; 5α-Pregnane-3α,17α-diol-20-one; (3α,5α,17α)-3,17-Dihydroxypregnan-20-one
EINECS	Contact for details

Quality Control

Our 5-α-Pregnan-3-Alpha, 17-Diol-20-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.