Description

3β,12β,14-Trihydroxy-5α-Card-20(22)-Enolide is a high-purity cardenolide derivative, a key structural motif in biologically active compounds. This specialized intermediate is valued for its precise stereochemistry and functional groups, which are critical for advanced pharmaceutical synthesis and research. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cardiac mechanisms.
• Medicinal Chemistry: Provides a scaffold for structure-activity relationship (SAR) studies to develop new compounds with targeted biological activity.
• API Development: Employed in the research and process development stages for active pharmaceutical ingredients (APIs) with cardenolide backbones.

Basic Information

Product Name	3β,12β,14-Trihydroxy-5α-Card-20(22)-Enolide
CAS No.	6875-15-6
Molecular Formula	C₂₃H₃₄O₅
Molecular Weight	390.51 g/mol
Synonyms	3β,12β,14-Trihydroxy-5α-card-20(22)-enolide; 3β,12β,14-Trihydroxy-5α-cardenolide; 5α-Card-20(22)-enolide-3β,12β,14-triol; (3β,5α,12β)-3,12,14-Trihydroxycard-20(22)-enolide; 3β,12β,14-Trihydroxy-5α-card-20(22)-enolide (Cardenolide derivative); 6875-15-6; Card-20(22)-enolide-3β,12β,14-triol, 5α-
EINECS	Contact for details

Quality Control

Our 3β,12β,14-Trihydroxy-5α-Card-20(22)-Enolide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.