Description

(25R)-Spirost-4-En-3-One CAS NO 6870-79-7 is a high-purity steroidal sapogenin derivative, specifically a spirostanone, that serves as a critical advanced intermediate in organic synthesis. Its value lies in its defined stereochemistry at the C-25 position, which is essential for producing compounds with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of steroid-based drugs, bioactive natural product analogs, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the semi-synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial labs for studying steroid biosynthesis, metabolism, and structure-activity relationships (SAR).
• Natural Product Synthesis: Serves as a chiral starting material for the total synthesis of complex natural products derived from plant sapogenins.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC or GC method development and validation.
• Biochemical Probes: Potential use in developing enzyme inhibitors or probes for biological pathways involving steroid receptors.

Basic Information

Product Name	(25R)-Spirost-4-En-3-One
CAS No.	6870-79-7
Molecular Formula	C27H40O3
Molecular Weight	412.61 g/mol
Synonyms	(25R)-Spirost-4-en-3-one; 25R-Spirost-4-en-3-one; (25ξ)-Spirost-4-en-3-one; 3-Oxospirost-4-ene; Tigogenone; (25R)-3-Oxo-5α-spirostan; 5α-Spirostan-3-one, δ4-; Tigogenin ketone
EINECS	229-959-5

Quality Control

Our (25R)-Spirost-4-En-3-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.