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3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,11α,14-Trihydroxy-5β-Card-20(22)-Enolide CAS NO 6869-51-8


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CAS No.:6869-51-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,11α,14-Trihydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a class of compounds known for their potent biological activity. This compound is valued for its role as a critical reference standard and a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on cardiovascular therapeutics and natural product chemistry. Our supply ensures consistent quality and reliable availability for your critical projects.

Application

  • Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of cardiac glycosides in research and quality control laboratories.
  • Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of specialized cardiovascular drugs.
  • Biochemical Research: Employed in studies investigating the mechanism of action of Na+/K+-ATPase inhibition and related cardiac effects.
  • Natural Product Isolation & Synthesis: Acts as a benchmark compound in the isolation, purification, and total synthesis of complex steroidal glycosides.
  • Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) for cardiac glycoside detection.

Basic Information

Item Detail
Product Name 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,11α,14-Trihydroxy-5β-Card-20(22)-Enolide
CAS No. 6869-51-8
Molecular Formula C29H44O9
Molecular Weight 536.66 g/mol
Synonyms Gitoxin; 16-Formylgitoxigenin 3-O-α-L-diginoside; Anhydrogitalin; Bigitalin; Pseudodigitoxin; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,11α,14-trihydroxy-5β,14β-card-20(22)-enolide; 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,11,14-trihydroxy-19-oxo-5β-card-20(22)-enolide
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Quality Control

Every batch of 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-5,11α,14-Trihydroxy-5β-Card-20(22)-Enolide is manufactured and tested under strict quality management systems. We ensure compliance with high-purity standards suitable for pharmaceutical research. Comprehensive testing includes identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 2.0%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Unknown Impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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