Description

Heptamethonium CAS NO 6810-45-3 is a bis-quaternary ammonium compound, specifically a heptamethylene bis(trimethylammonium) salt, known for its potent ganglionic blocking activity. This compound is of significant interest in pharmacological research and development due to its role as a classic nicotinic acetylcholine receptor antagonist. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those focused on autonomic nervous system studies, neuromuscular research, and the synthesis of novel therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard and tool compound in studies of ganglionic blockade and nicotinic acetylcholine receptor (nAChR) function.
• Neuroscience & Neuropharmacology: Employed in experimental models to investigate autonomic nervous system regulation and synaptic transmission.
• Chemical Synthesis: Serves as a key intermediate or building block in the synthesis of more complex quaternary ammonium compounds and potential drug candidates.
• Academic & Institutional Research: Utilized in university and institutional labs for teaching and advanced research in medicinal chemistry and physiology.
• Biochemical Assay Development: Acts as a control or standard in the development and validation of assays targeting ion channels and receptors.

Basic Information

Product Name	Heptamethonium
CAS No.	6810-45-3
Molecular Formula	C13H30N2
Molecular Weight	214.40 g/mol
Synonyms	Heptamethylene-1,7-bis(trimethylammonium); C7; Heptamethonium diiodide; 1,7-Heptanediylbis(trimethylammonium); Hexamethonium homologue; NSC 169944; Trimethyl(7-trimethylammonioheptyl)ammonium
EINECS	Contact for details

Quality Control

Our Heptamethonium is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We support cGMP and ISO guided practices for reliable and consistent material supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.