Description

2,3-Dihydro-1,4-Benzodioxine-6-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound matters as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce the 1,4-benzodioxane moiety into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the benzodioxane structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and polymers with unique optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing client-specific compounds.

Basic Information

Product Name	2,3-Dihydro-1,4-Benzodioxine-6-Carbonyl Chloride
CAS No.	6761-70-2
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	1,4-Benzodioxane-6-carbonyl chloride; 6-(Chlorocarbonyl)-2,3-dihydro-1,4-benzodioxine; 2,3-Dihydro-1,4-benzodioxin-6-carbonyl chloride; 1,4-Benzodioxan-6-carbonyl chloride; 6-Carboxy-2,3-dihydro-1,4-benzodioxine chloride; 6-Chlorocarbonyl-2,3-dihydrobenzo[1,4]dioxine
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1,4-Benzodioxine-6-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.