Description

(3Ar)-2,3,3Aα,4,4A,5,7Aα,8,9,9Aα-Decahydro-4Aβ,8α-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2,5-Dione is a high-purity, complex sesquiterpene lactone derivative with a unique fused ring structure. This compound is valued for its role as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical candidates. It is essential for R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to build sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex sesquiterpenoids and other natural products for biological evaluation.
• Agrochemical Research: Serves as a precursor for developing new active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probe: Utilized as a scaffold or starting point for creating molecular probes to study biological pathways and protein interactions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique thermal or optical properties.
• Academic & Industrial R&D: A valuable compound for methodological development in organic synthesis, including catalysis and stereoselective transformations.

Basic Information

Product Name	(3Ar)-2,3,3Aα,4,4A,5,7Aα,8,9,9Aα-Decahydro-4Aβ,8α-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2,5-Dione
CAS No.	6754-14-9
Molecular Formula	C₁₅H₁₈O₃
Molecular Weight	246.30 g/mol
Synonyms	2,5-Dioxo-3-methylenedecahydroazuleno[6,5-b]furan; 3-Methylene-2,5-dioxodecahydroazuleno[6,5-b]furan; Azuleno[6,5-b]furan-2,5-dione, decahydro-4a,8-dimethyl-3-methylene-, (3aR,4aS,7aS,9aS)-rel-; (rel-(3aR,4aS,7aS,9aS))-Decahydro-4a,8-dimethyl-3-methyleneazuleno[6,5-b]furan-2,5-dione; Sesquiterpene lactone derivative; Advanced sesquiterpenoid intermediate.
EINECS	Contact for details

Quality Control

Every batch of our (3Ar)-2,3,3Aα,4,4A,5,7Aα,8,9,9Aα-Decahydro-4Aβ,8α-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2,5-Dione is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.