Description

7-Amino-3-β-D-Ribofuranosyl-1H-Pyrazolo[4,3-D]Pyrimidine Monohydrate is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate for the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleoside metabolism. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality raw materials for active pharmaceutical ingredient (API) synthesis and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid synthesis.
• Antiviral Drug Development: Serves as a core scaffold for developing novel therapeutics against viral infections.
• Oncology Research: Investigated for its potential as a chemotherapeutic agent or as a building block for targeted cancer therapies.
• Process Chemistry: Employed in route scouting and scale-up processes for the manufacture of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	7-Amino-3-β-D-Ribofuranosyl-1H-Pyrazolo[4,3-D]Pyrimidine Monohydrate
CAS No.	6742-12-7
Molecular Formula	C10H14N6O5 • H2O
Molecular Weight	316.27 g/mol
Synonyms	7-Amino-3-β-D-ribofuranosyl-1H-pyrazolo[4,3-d]pyrimidine Monohydrate; 7-Amino-3-(β-D-ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine Hydrate; Tubercidin Impurity; 7-Amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine Hydrate; 7-Amino-3-(β-D-ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine; 7-Amino-3-(β-D-ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine Monohydrate; 7-Amino-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine; 7-Amino-3-(β-D-ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine (Monohydrate)
EINECS	Contact for details

Quality Control

Our 7-Amino-3-β-D-Ribofuranosyl-1H-Pyrazolo[4,3-D]Pyrimidine Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.5% - 6.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.