Description

3-Deazaadenosine is a synthetic nucleoside analog and a potent inhibitor of S-adenosylhomocysteine hydrolase (SAH hydrolase). This compound is a critical research tool for studying cellular methylation processes, epigenetics, and viral replication mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on antiviral drug discovery, oncology research, and metabolic pathway analysis.

Application

• Biochemical Research: A key reagent for studying methylation pathways and S-adenosylhomocysteine (SAH) metabolism in cellular systems.
• Antiviral Drug Discovery: Investigated for its potential to inhibit the replication of various viruses by interfering with viral mRNA cap methylation.
• Epigenetics & Oncology Research: Used to modulate cellular methylation patterns, making it valuable for studying gene expression and cancer cell proliferation.
• Enzyme Inhibition Studies: Serves as a standard inhibitor for SAH hydrolase in enzymatic assays and mechanistic studies.
• Pharmaceutical Intermediate: Acts as a building block or precursor in the synthesis of more complex nucleoside-based therapeutic agents.
• Cell Culture & Microbiology: Employed in media to study the effects of methylation inhibition on bacterial or eukaryotic cell growth and function.

Basic Information

Product Name	3-Deazaadenosine
CAS No.	6736-58-9
Molecular Formula	C11H14N4O4
Molecular Weight	266.25 g/mol
Synonyms	3-Deazaadenosine; 3-Deaza-Ado; 9-β-D-Ribofuranosyl-3-deazaadenine; 3-Deaza-adenosine; 3-Deazapurine riboside; 3-DAA; Tubercidin analog; 3-Deazapurine nucleoside; 3-Deaza-9H-purin-6-amine riboside
EINECS	Contact for details

Quality Control

Our 3-Deazaadenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.