Description

2',5'-Dideoxyadenosine is a modified nucleoside analog of adenosine, where hydroxyl groups at the 2' and 5' positions of the ribose sugar are replaced by hydrogen atoms. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex nucleotide derivatives and potential pharmaceutical agents. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, biochemical research, and diagnostic reagent synthesis.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving adenosine deaminase, kinases, and other nucleotide-metabolizing enzymes.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Diagnostic Reagents: Employed in the development of diagnostic kits and assays that detect or quantify specific enzymatic activities.
• Life Science Tools: Incorporated into probes or labeled compounds for studying cellular signaling pathways, such as those involving cyclic AMP.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for pharmaceutical and research applications.

Basic Information

Product Name	2',5'-Dideoxyadenosine
CAS No.	6698-26-6
Molecular Formula	C10H13N5O2
Molecular Weight	235.25 g/mol
Synonyms	2',5'-Dideoxyadenosine; 9-[(2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl]-9H-purin-6-amine; 2',5'-ddA; DDA; 2',5'-Dideoxy-Adenosine; Adenosine, 2',5'-dideoxy-; 6-Amino-9-(2,5-dideoxy-β-D-erythro-pentofuranosyl)-9H-purine
EINECS	229-761-3

Quality Control

Our 2',5'-Dideoxyadenosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.