Description

5-Bromo-2'-Deoxyuridine 5'-Monophosphate is a halogenated nucleotide monophosphate analog, a critical biochemical building block for research and development. This compound is valued for its ability to incorporate into nucleic acids, making it an essential tool for studying DNA synthesis, repair mechanisms, and as a potential antiviral or anticancer agent. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in molecular biology, enzymology, and medicinal chemistry.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies of DNA polymerases, kinases, and other nucleic acid-metabolizing enzymes.
• Antiviral/Anticancer Agent Development: Serves as a precursor in the synthesis of nucleoside analogs for screening therapeutic activity against viral infections and tumors.
• DNA Labeling and Detection: Can be utilized in techniques for radioisotopic or fluorescent labeling of DNA probes for hybridization assays.
• Cell Biology Studies: Employed to investigate cell proliferation, DNA replication, and the mechanisms of action of related chemotherapeutic drugs.
• Diagnostic Reagent Manufacturing: A key raw material in the production of diagnostic kits and reagents for molecular diagnostics.

Basic Information

Product Name	5-Bromo-2'-Deoxyuridine 5'-Monophosphate
CAS No.	6666-38-2
Molecular Formula	C10H14BrN2O8P
Molecular Weight	409.11 g/mol
Synonyms	5-Bromo-2'-deoxyuridine 5'-monophosphate; 5-BrdUMP; 5-Bromo-dUMP; BrdUMP; 5-Bromo-2'-deoxyuridylic acid; 5-Bromodeoxyuridine 5'-monophosphate; 5-Bromo-1-(2-deoxy-β-D-erythro-pentofuranosyl)uracil 5'-phosphate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2'-Deoxyuridine 5'-Monophosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.