Description

o-Nitrobenzenesulfonyl Azide is a versatile and highly reactive organic azide compound, primarily valued as a key reagent in organic synthesis. Its core function is to serve as a safe and efficient source of nitrene equivalents or as a sulfonylating agent, enabling critical transformations in complex molecule construction. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it facilitates the synthesis of novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for the preparation of sulfonamides and other nitrogen-containing heterocycles, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its ability to introduce sulfonyl and azide functionalities.
• Polymer & Materials Science: Employed as a cross-linking agent or functional monomer in the development of specialty polymers, coatings, and advanced materials with tailored properties.
• Click Chemistry: Acts as a precursor for generating reactive intermediates used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other bioorthogonal reactions for bioconjugation and labeling.
• Organic Methodology Research: A fundamental tool in academic and industrial R&D for developing new synthetic routes involving C-H amination, sulfonylation, and nitrene transfer reactions.
• Dye & Pigment Manufacturing: Utilized in the synthesis of complex aromatic sulfonamide derivatives that serve as intermediates for high-performance dyes and pigments.

Basic Information

Product Name	o-Nitrobenzenesulfonyl Azide
CAS No.	6655-31-8
Molecular Formula	C6H4N4O4S
Molecular Weight	228.18 g/mol
Synonyms	2-Nitrobenzenesulfonyl Azide; o-Nitrobenzenesulfonazide; 2-Nitrobenzenesulfonazide; Benzenesulfonyl azide, 2-nitro-; ONBSA; 2-Nitrobenzene-1-sulfonyl azide; Azido(2-nitrophenyl)methanesulfonate; (2-Nitrophenyl)sulfonyl azide
EINECS	Contact for details

Quality Control

Our o-Nitrobenzenesulfonyl Azide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Due to its nature as an organic azide, it should be stored separately from incompatible materials and sources of heat or ignition. Keep container tightly sealed under an inert atmosphere to minimize decomposition.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.