Description

1-Trimethylsiloxy-1,3-Butadiene is a versatile organosilicon compound, specifically a silyl enol ether derivative of butadiene. This chemical is a valuable synthetic intermediate, prized for its role in facilitating carbon-carbon bond formation and protecting group chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for cycloaddition and annulation reactions.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides.
• Polymer & Material Science: Serves as a monomer or modifier in the development of specialty silicones and functional polymers.
• Organic Synthesis Reagent: Acts as a diene component in Diels-Alder reactions and as a nucleophile in Michael additions.
• Flavor & Fragrance Industry: Employed in the synthesis of complex terpenoids and aroma chemicals.
• Research & Development: A crucial reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	1-Trimethylsiloxy-1,3-Butadiene
CAS No.	6651-43-0
Molecular Formula	C7H14OSi
Molecular Weight	142.27 g/mol
Synonyms	1,3-Butadiene, 1-(trimethylsiloxy)-; 1-(Trimethylsilyloxy)-1,3-butadiene; Danishefsky's Diene; (1-Methoxy-3-trimethylsilyloxy-1,3-butadiene); TMS enol ether of 1,3-butadien-1-ol; 1-Trimethylsilyloxy-1,3-butadiene; 1-(Trimethylsiloxy)-1,3-butadiene
EINECS	229-682-8

Quality Control

Our 1-Trimethylsiloxy-1,3-Butadiene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.