Description

2-Methyl-1-(Trimethylsiloxy)-1-Propene is a versatile organosilicon compound, specifically a silyl enol ether, valued for its role as a key synthetic intermediate in organic synthesis. Its primary commercial importance lies in its ability to act as a protected enolate equivalent, facilitating controlled carbon-carbon bond formation under mild conditions. This makes it an essential reagent for R&D chemists and production units in the pharmaceutical, agrochemical, and advanced materials sectors seeking efficient and selective synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug molecules, particularly for introducing specific carbonyl-containing fragments via aldol and Michael addition reactions.
• Agrochemical Synthesis: Used in the production of active ingredients for pesticides and herbicides, where its reactivity enables the construction of specific stereocenters and carbon chains.
• Fine Chemical Production: Employed in the manufacture of flavors, fragrances, and specialty chemicals requiring precise molecular architecture.
• Polymer & Material Science: Serves as a monomer or modifying agent in the development of specialty silicones and functional polymers with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization in pilot-scale operations.

Basic Information

Product Name	2-Methyl-1-(Trimethylsiloxy)-1-Propene
CAS No.	6651-34-9
Molecular Formula	C7H16OSi
Molecular Weight	144.29 g/mol
Synonyms	1-Propene, 2-methyl-1-(trimethylsiloxy)-; 2-Methyl-1-(trimethylsilyloxy)-1-propene; 2-Methyl-1-trimethylsiloxypropene; 1-Trimethylsiloxy-2-methylpropene; (2-Methyl-1-propenyloxy)trimethylsilane; Silyl enol ether of isobutyraldehyde; Trimethyl(2-methyl-1-propenyloxy)silane; Isobutyraldehyde trimethylsilyl enol ether
EINECS	229-676-3

Quality Control

Our production of 2-Methyl-1-(Trimethylsiloxy)-1-Propene adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including assay by GC or HPLC and identity confirmation by IR and NMR spectroscopy. Certificates of Analysis (COA) detailing purity and impurity profiles are provided with every shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition and maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.