Description

2',3',5'-Trideoxyadenosine is a synthetic nucleoside analog, a modified derivative of adenosine where the hydroxyl groups on the 2', 3', and 5' carbons of the ribose sugar are replaced by hydrogen atoms. This structural modification makes it a valuable intermediate and building block in organic synthesis and medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates.
• Organic Synthesis: A versatile precursor for the preparation of more complex, modified nucleosides and oligonucleotides.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	2',3',5'-Trideoxyadenosine
CAS No.	6612-70-0
Molecular Formula	C10H13N5O
Molecular Weight	219.24 g/mol
Synonyms	2',3',5'-Trideoxyadenosine; 9-(2,3,5-Trideoxy-β-D-*erythro*-pentofuranosyl)adenine; 2',3',5'-Trideoxyadenosine; 2',3',5'-Trideoxyadenosine (9CI); Adenosine, 2',3',5'-trideoxy-; 2,3,5-Trideoxyadenosine; 9-(2,3,5-Trideoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine
EINECS	Contact for details

Quality Control

Our 2',3',5'-Trideoxyadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.