Description

Distamycin A Hydrochloride is a potent antiviral and antitumor antibiotic derived from *Streptomyces distallicus*. This compound is a key research tool and pharmaceutical intermediate, valued for its ability to bind specifically to the minor groove of DNA at AT-rich sequences. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical industries for drug discovery, molecular biology studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of more complex antiviral and anticancer drug candidates.
• Biochemical Research: Used extensively as a molecular probe to study DNA-protein interactions, chromatin structure, and gene regulation mechanisms.
• Antiviral Studies: Investigated for its activity against viruses such as herpes simplex and cytomegalovirus due to its DNA-binding properties.
• Antitumor Research: Employed in oncology research to understand and develop agents that interfere with DNA replication in cancer cells.
• Molecular Biology Reagent: Acts as a selective inhibitor in experiments designed to elucidate the function of AT-rich DNA sequences.

Basic Information

Product Name	Distamycin A Hydrochloride
CAS No.	6576-51-8
Molecular Formula	C22H29N7O5 • HCl
Molecular Weight	516.0 g/mol (as hydrochloride)
Synonyms	Distamycin A HCl; Distamycin A Hydrochloride; Antibiotic F 1510; NSC 116564; 1-Methyl-4-[1-methyl-4-[1-methyl-4-[[(formylamino)methyl]pyrrole-2-carboxamido]pyrrole-2-carboxamido]pyrrole-2-carboxamido]pyrrole-2-carboximidamide Hydrochloride; Berenil analog; Netropsin analog
EINECS	Contact for details

Quality Control

Our Distamycin A Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.