Description

18-Methyl-Estrone is a synthetic steroidal estrogen derivative, identified by CAS NO 6544-68-9. This compound is valued in advanced research and development for its specific hormonal activity profile, serving as a crucial intermediate or reference standard. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity fine chemicals for the development of novel therapeutic agents and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor binding, metabolism, and hormonal pathways.
• Academic & Clinical Research: Employed in university and institutional labs for fundamental endocrinology and steroid chemistry research.
• Fine Chemical Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs specializing in custom steroid synthesis.
• Analytical Standard: Provides a high-purity benchmark for developing and validating analytical methods (e.g., HPLC, LC-MS) in quality control laboratories.

Basic Information

Product Name	18-Methyl-Estrone
CAS No.	6544-68-9
Molecular Formula	C19H26O2
Molecular Weight	286.41 g/mol
Synonyms	18-Methylestrone; 13β-Ethyl-3-hydroxygona-1,3,5(10)-trien-17-one; 18-ME1; 18-Methyl-1,3,5(10)-estratrien-3-ol-17-one; 18-Methylestra-1,3,5(10)-trien-3-ol-17-one; 13β-Ethyl-17-oxo-1,3,5(10)-estratrien-3-ol
EINECS	Contact for details

Quality Control

Our 18-Methyl-Estrone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC-MS. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.