Description

(S)-5,6,7,8-Tetrahydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4B,8,8-Trimethylphenanthren-3(4Bh)-One is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure makes it a valuable chiral building block for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated molecular architectures into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those targeting steroid-like receptors or requiring specific three-dimensional frameworks.
• Advanced Organic Synthesis: Serves as a versatile building block for constructing polycyclic ring systems in medicinal chemistry and natural product synthesis.
• Agrochemical Research: Used in the development of new active ingredients with specific biological activities, leveraging its unique structural motifs.
• Material Science Precursor: Potential starting material for synthesizing specialized organic ligands or molecular components for advanced materials.
• Academic & Contract Research: A critical reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and chemical biology.

Basic Information

Product Name	(S)-5,6,7,8-Tetrahydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4B,8,8-Trimethylphenanthren-3(4Bh)-One
CAS No.	6467-01-2
Molecular Formula	C20H28O3
Molecular Weight	316.44 g/mol
Synonyms	(S)-4-Hydroxy-2-(1-hydroxy-1-methylethyl)-4b,8,8-trimethyl-5,6,7,8-tetrahydro-4bH-phenanthren-3-one; (S)-4-Hydroxy-2-(2-hydroxypropan-2-yl)-4b,8,8-trimethyl-4b,5,6,7,8,9-hexahydrophenanthren-3-one; (4bS)-4-Hydroxy-2-(1-hydroxy-1-methylethyl)-4b,8,8-trimethyl-5,6,7,8-tetrahydro-4bH-phenanthren-3-one; (S)-Hexahydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-4b,8,8-trimethylphenanthren-3(4bH)-one; (S)-4b,8,8-Trimethyl-4-hydroxy-2-(1-hydroxy-1-methylethyl)-5,6,7,8-tetrahydro-4bH-phenanthren-3-one; (S)-4b,8,8-Trimethyl-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,6,7,8-tetrahydro-4bH-phenanthren-3-one
EINECS	Contact for details

Quality Control

Our (S)-5,6,7,8-Tetrahydro-4-Hydroxy-2-(1-Hydroxy-1-Methylethyl)-4B,8,8-Trimethylphenanthren-3(4Bh)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.