Description

Xanthosine-5'-Triphosphate is a high-purity nucleotide triphosphate analog essential for biochemical research and development. This compound serves as a critical substrate and regulator in enzymatic studies, particularly those involving RNA polymerases and nucleotide-metabolizing enzymes. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, enzymology, and pharmaceutical discovery for investigating nucleotide metabolism and developing novel therapeutic agents.

Application

• Enzymatic Substrate for RNA Polymerases: Used as a substrate in in vitro transcription and RNA synthesis studies.
• Nucleotide Metabolism Research: A key reagent for studying purine salvage pathways, nucleotide interconversion, and enzyme kinetics.
• Biochemical Assay Development: Employed in the development of high-throughput screening assays for drug discovery targeting nucleotide-binding proteins.
• Structural Biology Studies: Used in X-ray crystallography and NMR to study protein-nucleotide interactions and enzyme active sites.
• Diagnostic Kit Manufacturing: A component in diagnostic kits for measuring enzyme activities related to purine metabolism.
• Precursor for Modified Nucleotides: Serves as a starting material for the chemical synthesis of other modified nucleotide analogs.

Basic Information

Item	Detail
Product Name	Xanthosine-5'-Triphosphate
CAS No.	6253-56-1
Molecular Formula	C10H15N4O14P3
Molecular Weight	508.16 g/mol
Synonyms	XTP; Xanthosine triphosphate; 5'-XTP; Xanthosine 5'-(tetrahydrogen triphosphate); Xanthine riboside triphosphate; 9-β-D-Ribofuranosylxanthine 5'-triphosphate
EINECS	Contact for details

Quality Control

Our Xanthosine-5'-Triphosphate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is analyzed for identity, purity, and the absence of critical contaminants such as nucleases. A comprehensive Certificate of Analysis (COA) detailing HPLC purity, NMR identification, and endotoxin levels is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg
Biological Activity	Functional in standard enzymatic assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.