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3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-1β,5,11α,14,19-Pentahydroxy-5β-Card-20(22)-Enolide CAS NO 6251-64-5


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CAS No.:6251-64-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-1β,5,11α,14,19-Pentahydroxy-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a class of compounds known for their potent biological activity. This compound is critical for pharmaceutical research and development, particularly in the study of cardiac function and the synthesis of specialized therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers focused on cardiovascular drug discovery and advanced organic synthesis.

Application

  • Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in drug manufacturing.
  • Cardiovascular Research: Used as a key biochemical tool in pharmacological studies targeting ion channels and cardiac muscle contractility.
  • Active Pharmaceutical Ingredient (API) Intermediate: Acts as a crucial building block in the multi-step synthesis of complex cardiac therapeutics.
  • Biochemical Assay Development: Employed in the creation of high-throughput screening assays for drug discovery programs.
  • Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of glycoside compounds.
  • Metabolite Identification: Used as an analytical standard in ADME (Absorption, Distribution, Metabolism, and Excretion) studies for related drugs.

Basic Information

Product Name 3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-1β,5,11α,14,19-Pentahydroxy-5β-Card-20(22)-Enolide
CAS No. 6251-64-5
Molecular Formula C29H44O12
Molecular Weight 584.66 g/mol
Synonyms Desglucouzarin; Uzarigenin 3-O-6-deoxy-α-L-talopyranoside; 3β-[(6-Deoxy-α-L-talopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxy-5β-card-20(22)-enolide; NSC 176324; 6-Deoxy-α-L-talopyranoside, uzarigenin 3-O-; Uzarigenin 3-O-α-L-rhamnoside (common misnomer related to stereochemistry); 5β-Card-20(22)-enolide, 3-[(6-deoxy-α-L-talopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, (1β,3β,5β,11α)-
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Quality Control

Our 3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-1β,5,11α,14,19-Pentahydroxy-5β-Card-20(22)-Enolide is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Specific Optical Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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