Description

14-Hydroxycarda-3,5,20(22)-Trienolide is a high-purity steroidal lactone compound of significant interest in advanced pharmaceutical research and development. This specialized intermediate is valued for its role as a key building block in the synthesis of complex bioactive molecules, particularly within the cardiology and oncology therapeutic areas. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel cardiac glycosides and other steroidal drugs.
• Biochemical Research: Used as a reference standard or a starting material in studies investigating steroid biosynthesis pathways and receptor interactions.
• API Development: Serves as a key chiral building block for the development of new Active Pharmaceutical Ingredients (APIs) with potential cardioprotective or antitumor properties.
• Process Chemistry: Employed in process development and scale-up activities for the optimization of synthetic routes to complex natural product derivatives.

Basic Information

Product Name	14-Hydroxycarda-3,5,20(22)-Trienolide
CAS No.	6246-62-4
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	14-Hydroxycarda-3,5,20(22)-trienolide; 3β,14-Dihydroxycarda-5,20(22)-dienolide; 14-Hydroxy-3β-hydroxycarda-5,20(22)-dienolide; 14-Hydroxycardenolide derivative; Card-20(22)-enolide-3β,14-diol; (3β,5β,14β)-3,14-Dihydroxycard-20(22)-enolide; 14-Hydroxycardenolide
EINECS	Contact for details

Quality Control

Our 14-Hydroxycarda-3,5,20(22)-Trienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.