Description

2-(6-Benzylsulfanylpurin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is a high-purity nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of modified nucleotides and potential therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, anticancer therapies, and novel biochemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid processing.
• Proteomics & Genomics: Acts as a modified base for creating labeled nucleotides used in sequencing, PCR, and other molecular biology techniques.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2-(6-Benzylsulfanylpurin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol
CAS No.	6165-03-3
Molecular Formula	C₁₇H₁₈N₄O₄S
Molecular Weight	374.41 g/mol
Synonyms	6-(Benzylthio)-9-β-D-ribofuranosyl-9H-purine; 6-Benzylthio-9-β-D-ribofuranosylpurine; 6-Benzylmercaptopurine riboside; 6-Benzylthiopurine ribonucleoside; NSC 113195; 9-β-D-Ribofuranosyl-6-(benzylthio)-9H-purine; 6-Benzylsulfanyl-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purine
EINECS	Contact for details

Quality Control

Our 2-(6-Benzylsulfanylpurin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.