Description

Cyclohexylmethyl Chloroformate is a versatile and reactive chloroformate ester widely used as a key building block in organic synthesis. Its primary value lies in its role as a protecting and activating agent, particularly for the introduction of the cyclohexylmethoxycarbonyl (Cmoc) group, which is crucial in peptide and pharmaceutical intermediate manufacturing. This high-purity reagent is essential for research laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable and efficient synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for introducing the Cmoc protecting group in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a coupling agent and for the temporary protection of amine functionalities during solid-phase and solution-phase peptide synthesis.
• Agrochemical Production: Serves as a building block in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Employed in the synthesis and functionalization of polymers to impart specific chemical properties or to create specialized co-polymers.
• Organic Synthesis Reagent: Utilized in various organic transformations, including esterifications and carbonylations, as a source of the cyclohexylmethyloxycarbonyl moiety.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in exploring new synthetic routes and developing novel compounds.

Basic Information

Product Name	Cyclohexylmethyl Chloroformate
CAS No.	6099-86-1
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	Chloroformic Acid Cyclohexylmethyl Ester; Cyclohexylmethyl Chlorocarbonate; Cyclohexylmethyloxycarbonyl Chloride; Cmoc-Cl; (Cyclohexylmethoxy)carbonyl Chloride; Cyclohexanemethyl Chloroformate; Cyclohexylmethyl Carbonochloridate
EINECS	228-052-9

Quality Control

Our Cyclohexylmethyl Chloroformate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Purity (GC Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.