Description

N(4)-Methoxycytidine is a chemically modified nucleoside analog of cytidine, where a methoxy group is substituted at the N4 position. This specific modification is crucial for research in nucleic acid chemistry, enabling the study of base-pairing interactions, stability, and enzymatic recognition. It serves as a valuable building block and reference standard for pharmaceutical R&D, diagnostic assay development, and academic research in biochemistry and molecular biology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used to study RNA/DNA structure, function, and stability, particularly the effects of base modifications.
• Diagnostic Reagent Development: Acts as a component in the development of probes and assays for genetic testing and pathogen detection.
• Reference Standard: Serves as a high-purity analytical standard for quality control in the production of related nucleosides and oligonucleotides.
• Enzymology Studies: Utilized as a substrate or inhibitor to investigate the specificity and mechanism of nucleoside-metabolizing enzymes.
• Oligonucleotide Synthesis: Incorporated into synthetic oligonucleotides to modulate their properties for therapeutic or diagnostic applications.

Basic Information

Product Name	N(4)-Methoxycytidine
CAS No.	6082-19-5
Molecular Formula	C10H15N3O6
Molecular Weight	273.24 g/mol
Synonyms	4-Methoxycytidine; N4-Methoxycytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-4-methoxypyrimidin-2-one; Cytidine, N(4)-methoxy-; 4-Methoxy-1-β-D-ribofuranosyl-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our N(4)-Methoxycytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.