Description

4-Cyanobenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the dual functionality of the reactive acyl chloride group and the electron-withdrawing cyano substituent, enabling efficient acylation and subsequent functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for synthesizing active pharmaceutical ingredients (APIs), liquid crystal materials, and advanced polymers.

Application

• Pharmaceutical Intermediate: Key precursor for the synthesis of various active pharmaceutical ingredients (APIs), especially those containing benzamide or related structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the cyanobenzoyl moiety is required.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers, polyamides, and high-performance resins.
• Dye & Pigment Manufacturing: Intermediate for producing advanced dyes and organic pigments.
• Peptide & Protein Research: Used as an acylating agent in biochemical research and peptide synthesis.
• Cross-coupling Reactions: Valuable substrate in palladium-catalyzed cross-coupling reactions for creating complex biaryl structures.

Basic Information

Product Name	4-Cyanobenzoyl Chloride
CAS No.	6068-72-0
Molecular Formula	C8H4ClNO
Molecular Weight	165.58 g/mol
Synonyms	p-Cyanobenzoyl Chloride; 4-Cyanobenzoic Acid Chloride; p-Cyanobenzoic Acid Chloride; 4-Carboxybenzonitrile Chloride; Terephthalonitrile Monochloride; Benzonitrile, 4-(chlorocarbonyl)-; NSC 406079; 1-Cyano-4-(chlorocarbonyl)benzene
EINECS	228-001-5

Quality Control

Our 4-Cyanobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	95 - 100 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.