Description

n-Hydroxyisobutyrimidoyl Chloride is a versatile and highly reactive chemical intermediate, primarily valued for its role in the synthesis of heterocyclic compounds and functionalized amides. Its significance lies in its ability to act as a key building block for creating complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups with high efficiency.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various heterocyclic scaffolds found in drug candidates, including potential antivirals, antibiotics, and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive chloride and imidoyl groups enable the construction of novel active molecules.
• Peptide Mimetics & Bioactive Molecules: Employed to create peptidomimetics and other bioactive compounds that mimic natural peptides for therapeutic applications.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties, such as high thermal stability or specific reactivity.
• Material Science Research: Utilized in academic and industrial R&D for synthesizing novel organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Acts as a reagent for modifying proteins or nucleic acids, facilitating the creation of probes for studying biological mechanisms.

Basic Information

Product Name	n-Hydroxyisobutyrimidoyl Chloride
CAS No.	684-88-8
Molecular Formula	C4H8ClNO
Molecular Weight	121.56 g/mol
Synonyms	2-Hydroxy-2-methylpropanimidoyl Chloride; Isobutyrohydroxamic Acid Chloride; α-Hydroxyisobutyrimidoyl Chloride; N-Hydroxy-2-methylpropionimidoyl Chloride; 2-Methyl-2-hydroxypropionimidoyl Chloride; Hydroxyisobutyrimidoyl Chloride; 684-88-8; NSC 163049
EINECS	211-688-2

Quality Control

Our n-Hydroxyisobutyrimidoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.