Description

Di-tert-Butylphosphinic Acidchloride is a specialized organophosphorus compound widely used as a key intermediate in advanced chemical synthesis. Its value lies in its role as a versatile building block for introducing the sterically hindered di-tert-butylphosphinyl group, which is crucial for modifying material properties and creating complex molecular architectures. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it facilitates the development of novel catalysts, ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating phosphine oxide and phosphinic acid derivatives with potential therapeutic applications.
• Catalyst & Ligand Synthesis: Serves as a key building block for manufacturing sterically demanding phosphine ligands, which are essential in homogeneous catalysis for fine chemical and polymer production.
• Agrochemical Development: Used in the research and production of advanced crop protection agents, where the phosphinic acid chloride moiety can impart specific biological activity and stability.
• Polymer Modification: Employed to introduce phosphinate groups into polymer backbones or as chain terminators, enhancing flame retardancy, adhesion, or thermal stability of specialty plastics and resins.
• Material Science Research: A valuable reagent for developing new organophosphorus compounds with applications in electronics, optics, and as additives for advanced materials.
• Chemical Synthesis Reagent: Functions as a phosphorylating agent in organic synthesis for the preparation of esters, amides, and other phosphorus-containing target molecules in laboratory and pilot-scale operations.

Basic Information

Item	Detail
Product Name	Di-tert-Butylphosphinic Acidchloride
CAS No.	677-74-7
Molecular Formula	C8H18ClOP
Molecular Weight	196.65 g/mol
Synonyms	Di-tert-butylphosphinic chloride; Di-tert-butylphosphinyl chloride; P,P-Di-tert-butylphosphinic chloride; Chlorodi-tert-butylphosphine oxide; Di-tert-butylphosphinous acid chloride; (tert-Butyl)2P(O)Cl; Bis(1,1-dimethylethyl)phosphinic chloride
EINECS	211-650-5

Quality Control

Our Di-tert-Butylphosphinic Acidchloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and industrial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.